Research Works

Our Research

Each year our medical review panels carefully assess the many applications we receive from the teams in the hospitals and universities around the UK needing grants to help them progress their work into understanding, diagnosing and treating the country’s biggest killer, heart disease.

Heart Research UK is a national charity which spends its funding on activity across the country, which means what is raised locally is used to help hearts near you.





Overwriting blood vessel identity to prevent graft failure

Dr Denise McDonald, Queen’s University Belfast

New drugs to improve blood supply to the heart in patients suffering a heart attack

Prof Paolo Madeddu, University of Bristol

Pregnancy outcomes in women with cardiomyopathy

Dr Matthew Cauldwell, Chelsea and Westminster Hospital

Can heart disease patients taking part in cardiac rehabilitation be encouraged to stay active for longer?

Dr Nicole Blackburn, Ulster University

Improving access to cardiac rehabilitation for people with heart failure in Scotland

Prof Rod Taylor, University of Glasgow

Eliminating ‘zombie’ cells in your heart could alleviate age-related cardiac deterioration

Dr Georgina Ellison-Hughes, King’s College London

A new tool for predicting risk of cardiovascular event or death in patients who have suffered a heart attack

Prof Mamas A Mamas, University of Manchester

Why does heart failure make our muscles become smaller and weaker?

Dr T Scott Bowen, University of Leeds

Using wave intensity analysis to benefit patients with advanced heart failure

Dr Sern Lim, Queen Elizabeth Hospital Birmingham

A new technology for implanted electrical heart pumps in the treatment of heart failure

Prof Omar Escalona, Ulster University

New methods to detect heart failure ‘before it happens’ and develop strategies to prevent it

Dr Pierpaolo Pellicori, Queen Elizabeth University Hospital and University of Glasgow

A heart disease registry for Northern Ireland

Dr Anna Gavin, Queen’s University Belfast

Investigating the ‘cardiotoxic’ effects of cobalt in patients with hip replacements

Dr Susan Currie, University of Strathclyde

Stopping cancer patients getting heart disease

Prof Robin Plevin, University of Strathclyde

Detecting hidden markers to investigate and diagnose diabetic vascular disease

Dr Andrew Smith, University of Leeds

Metal fingerprinting in coronary heart disease for better diagnosis and treatment

Prof Giovanni Mann, King’s College London

‘Pre-habilitation’ in elderly patients undergoing cardiac surgery

Mr Enoch Akowuah, South Tees NHS Hospitals Foundation Trust

Investigating who is at risk of developing or dying from infective endocarditis

Prof Martin Thornhill, University of Sheffield

Developing a genetic test to improve the success of stem cell treatment for heart disease

Dr Enca Martin-Rendon, University of Oxford

Treating heart attacks using cell therapy

Prof Paolo Madeddu, University of Bristol

Developing new imaging techniques for coronary heart disease

Dr Richard Siow, King’s College London

Investigating the benefits and risks of using electronic cigarettes as an aid to stop smoking

Dr Markos Klonizakis, Sheffield Hallam University

Making every donor heart count

Mr Steven Tsui, Papworth Hospital NHS Foundation Trust, Cambridge

Next generation diagnosis of coronary heart disease using ‘deep learning’

Dr Jack Lee, King’s College London

Developing a new blood test to identify high-risk patients following treatment for a heart attack

Prof Ioakim Spyridopoulos, Newcastle University

Developing a new imaging method to study blood supply to a thickened heart

Dr Erica Dall’Armellina University of Leeds

Investigating the role of the ‘basement membrane’ in heart disease

Dr Tom Van Agtmael, University of Glasgow

A new treatment to prevent kidney damage in people undergoing angiography

Prof Amrita Ahluwalia, William Harvey Research Institute

Could UDCA be a new antifibrotic therapy for chronic heart failure?

Prof Julia Gorelik, Imperial College London

Reducing vein graft failure following heart bypass surgery

Prof Sarah George, University of Bristol

Using biological gases to control abnormal heart rhythms

Prof Derek Steele, University of Leeds

Studying how DNA is expressed in diseased hearts

Dr Chris Watson, Queen’s University Belfast

Novel treatment for ‘pseudoaneurysms’ in the groin

Prof Ashok Handa, Prof Eleanor Stride and Dr Regent Lee, University of Oxford

Imaging the heart in children born with heart disease - the 5-minute magnetic resonance scan

Dr Vivek Muthurangu, University College London and Great Ormond Street Hospital

Detecting heart muscle stiffening early

Prof Stuart Cook, Imperial College London

Building new blood vessels to treat babies with structural defects of the heart

Prof Paolo Madeddu, Bristol Heart Institute

The benefits of breaking up prolonged sedentary time on heart disease risk in people with spinal cord injury

Dr Daniel Bailey, University of Bedfordshire

Blood platelets and inflammation in heart disease

Prof Khalid Naseem, University of Leeds

Reducing inflammation to protect against heart and blood vessel disease

Prof Faisel Khan, University of Dundee

Can 'small RNA' molecules prevent build-up of fats in arteries?

Prof Annette Graham, Glasgow Caledonian University

Exercise to reduce heart disease risk: which type of exercise programme is most suitable for people with a kidney transplant?

Dr Nicolette Bishop, Loughborough University and University Hospitals of Leicester NHS Trust

Developing a novel ECG-based test to measure the risk of sudden cardiac death

Prof G André Ng, University of Leicester.

Developing new MRI techniques for microscopic insights into heart muscle structure.

Prof David Firmin and Dr Andrew Scott, Royal Brompton Hospital and Imperial College London