Medical Research Project

Coronary artery bypass surgery after myocardial infarction: identifying clinical outcomes by analysing the senescence associated secretory phenotype (non-clinical)

Understanding how ageing heart cells affect recovery after a heart attack

In progress

29/02/2024

North East

Diagnostic

Awarded amount: £110,105

Grant scheme: PhD

Institution: Newcastle University

Principle Investigator: Dr Gavin Richardson


Heart attacks, caused by blockages in the coronary arteries, cause a lack of blood to the heart.

Damage can persist even after the blockage is removed, potentially causing heart failure. Rapid ageing of heart cells after a heart attack causes the release of proteins which contribute to this damage.
This project is going to explore whether measuring the levels of these proteins in a patient’s blood is a good predictor of recovery from a heart attack.

This will provide insight into how to improve post-heart attack recovery and reduce the chance of heart failure.

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