Plaques in coronary heart disease
Aetiology
Coronary heart disease (CHD) is one of the single biggest killers in the UK and worldwide.
In CHD, fat builds up the blood vessels forming so called “plaques”. If these plaques break up or burst, they can cause blood clots, leading to a heart attack or stroke. It has been found that a sticky molecule called Lipoprotein a (Lp(a)) affects how likely a plaque is to break up.
This project will use novel imaging techniques to look at this molecule’s role within plaques. This will increase understanding of why plaques break up the way they do and provide potential targets for treatment.
The development of a new AI-supported model for imaging the heart based on data from over 700 people with atrial fibrillation, allow ablation to be more personalised to individual patients.
Cardiac patches for heart repair
A trial for every patient
Personalised angina care
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