Inflammation in narrowed blood vessels
Drug discovery / Therapeutics
When blood vessels become narrowed, it can lead to heart attack and stroke.
This is caused by atherosclerosis which is due to a combination of build-up of fatty deposits within the blood vessel walls and the immune system reacting to these deposits, called inflammation. This project will test whether a protein called “interleukin-2” can reduce inflammation and atherosclerosis.
This could lead to the development of new treatments of the underlying process that causes heart attack and stroke.
The development of a new AI-supported model for imaging the heart based on data from over 700 people with atrial fibrillation, allow ablation to be more personalised to individual patients.
Bringing together patients and medical professionals to establish a partnership aimed at identifying areas of priority in adult cardiac surgery, to better inform clinicians and make heart surgery safer for patients.
Developing an AI-assisted computer programme to identify whether a conduction system pacing (CSP) procedure has been successful, which will allow more patients to benefit from this innovative pacemaker technology.
Developing a new test to measure the levels of desmosine in the body, which are higher when there is damage to the aorta, to diagnose aortic dissection more quickly.
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